Molecular and epidemiological characterization of Plasmodium vivax recurrent infections in southern Mexico.

ABSTRACT:

Background

In southern Mexico, malaria transmission is low, seasonal, and persistent. Because many patients are affected by two or more malaria episodes caused by Plasmodium vivax, we carried out a study to determine the timing, frequency, and genetic identity of recurrent malaria episodes in the region between 1998 and 2008.

Methods

Symptomatic patients with more than one P. vivax infection were followed up, and blood samples were collected from primary and recurrent infections. DNA extracted from infected blood samples was analyzed for restriction fragment length polymorphism (RFLP) in genes encoding csp and msp3α, as well as size variation in seven microsatellites.

Results

One hundred and forty six parasite samples were collected from 70 patients; of these, 65 pati

SUBMITTER: Gonzalez-Ceron L 

PROVIDER: S-EPMC3637411 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature