CamMedNP: building the Cameroonian 3D structural natural products database for virtual screening.

ABSTRACT:

Background

Computer-aided drug design (CADD) often involves virtual screening (VS) of large compound datasets and the availability of such is vital for drug discovery protocols. We present CamMedNP - a new database beginning with more than 2,500 compounds of natural origin, along with some of their derivatives which were obtained through hemisynthesis. These are pure compounds which have been previously isolated and characterized using modern spectroscopic methods and published by several research teams spread across Cameroon.

Description

In the present study, 224 distinct medicinal plant species belonging to 55 plant families from the Cameroonian flora have been considered. About 80 % of these have been previously published and/or referenced in internationally recognized jo

SUBMITTER: Ntie-Kang F 

PROVIDER: S-EPMC3637470 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature