RNA sequencing reveals small RNAs differentially expressed between incipient Japanese threespine sticklebacks.

ABSTRACT:

Background

Non-coding small RNAs, ranging from 20 to 30 nucleotides in length, mediate the regulation of gene expression and play important roles in many biological processes. One class of small RNAs, microRNAs (miRNAs), are highly conserved across taxa and mediate the regulation of the chromatin state and the post-transcriptional regulation of messenger RNA (mRNA). Another class of small RNAs is the Piwi-interacting RNAs, which play important roles in the silencing of transposons and other functional genes. Although the biological functions of the different small RNAs have been elucidated in several laboratory animals, little is known regarding naturally occurring variation in small RNA transcriptomes among closely related species.

Results

We employed next-generation sequen

SUBMITTER: Kitano J 

PROVIDER: S-EPMC3637797 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature