The rationale and design of the Surgical Treatment for Ischemic Heart Failure (STICH) trial.

ABSTRACT:

Objectives

The rationale and design of the Surgical Treatment for Ischemic Heart Failure trial is described. Before the Surgical Treatment for Ischemic Heart Failure trial, less than 1000 patients with ischemic cardiomyopathy had been studied in randomized comparisons of medical therapy versus coronary artery bypass grafting. Trial data reflect how these therapies were delivered more than 20 years ago and do not indicate the relative benefits of medical therapy versus coronary artery bypass grafting in contemporary practice.

Methods

Randomization of consenting patients with heart failure, left ventricular ejection fraction of 0.35 or less, and coronary artery disease is based on whether patients are judged by attending physicians to be candidates only for coronary artery byp

SUBMITTER: Velazquez EJ 

PROVIDER: S-EPMC3638867 | biostudies-literature | 2007 Dec

REPOSITORIES: biostudies-literature