Behavioural profiles in captive-bred cynomolgus macaques: towards monkey models of mental disorders?

ABSTRACT:

Background

To date, experimental and preclinical studies on neuropsychiatric conditions have almost exclusively been performed in experimentally-induced animal models and have only rarely relied upon an ethological approach where animals have been observed in more naturalistic settings. The laboratory species of choice has been the rodent while the potential of more closely-related non-human primates have remained largely underexplored.

Methods

The present study, therefore, aimed at investigating the possible existence of spontaneous atypical/abnormal behaviours displayed by 40 cynomolgus macaques in captive conditions using an unbiased ethological scan-sampling analysis followed by multifactorial correspondence analysis and a hierarchical clustering.

Results

The stud

SUBMITTER: Camus SM 

PROVIDER: S-EPMC3639229 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature