OpenStructure: an integrated software framework for computational structural biology.

ABSTRACT: Research projects in structural biology increasingly rely on combinations of heterogeneous sources of information, e.g. evolutionary information from multiple sequence alignments, experimental evidence in the form of density maps and proximity constraints from proteomics experiments. The OpenStructure software framework, which allows the seamless integration of information of different origin, has previously been introduced. The software consists of C++ libraries which are fully accessible from the Python programming language. Additionally, the framework provides a sophisticated graphics module that interactively displays molecular structures and density maps in three dimensions. In this work, the latest developments in the OpenStructure framework are outlined. The extensive capabilities o

SUBMITTER: Biasini M 

PROVIDER: S-EPMC3640466 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature