Concerning the timing of antibiotic administration in women undergoing caesarean section: a systematic review and meta-analysis.

ABSTRACT: To assess the effects on maternal infectious morbidity and neonatal outcomes of the timing of antibiotic prophylaxis in women undergoing caesarean section. A recent National Institute for Health and Clinical Excellence (NICE) guideline reported that antibiotic administration before skin incision reduces the risk of maternal infection; this recommendation was based on a meta-analysis, however one including trials that were not double blind and not including a trial published recently. Systematic review and meta-analysis. Searches of PubMed and EMBASE and reference lists of the retrieved articles. Randomised double-blind controlled trials comparing the administration of antibiotics before skin incision with administration after cord clamping. Data on maternal total infectious morbidity, endo

SUBMITTER: Heesen M 

PROVIDER: S-EPMC3641422 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature