The effect of connective tissue material uncertainties on knee joint mechanics under isolated loading conditions.

ABSTRACT: Although variability in connective tissue parameters is widely reported and recognized, systematic examination of the effect of such parametric uncertainties on predictions derived from a full anatomical joint model is lacking. As such, a sensitivity analysis was performed to consider the behavior of a three-dimensional, non-linear, finite element knee model with connective tissue material parameters that varied within a given interval. The model included the coupled mechanics of the tibio-femoral and patello-femoral degrees of freedom. Seven primary connective tissues modeled as non-linear continua, articular cartilages described by a linear elastic model, and menisci modeled as transverse isotropic elastic materials were included. In this study, a multi-factorial global sensitivity analy

SUBMITTER: Dhaher YY 

PROVIDER: S-EPMC3641768 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature