Significance of anaerobes and oral bacteria in community-acquired pneumonia.

ABSTRACT:

Background

Molecular biological modalities with better detection rates have been applied to identify the bacteria causing infectious diseases. Approximately 10-48% of bacterial pathogens causing community-acquired pneumonia are not identified using conventional cultivation methods. This study evaluated the bacteriological causes of community-acquired pneumonia using a cultivation-independent clone library analysis of the 16S ribosomal RNA gene of bronchoalveolar lavage specimens, and compared the results with those of conventional cultivation methods.

Methods

Patients with community-acquired pneumonia were enrolled based on their clinical and radiological findings. Bronchoalveolar lavage specimens were collected from pulmonary pathological lesions using bronchoscopy and eval

SUBMITTER: Yamasaki K 

PROVIDER: S-EPMC3646017 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature