Nodding syndrome in Ugandan children--clinical features, brain imaging and complications: a case series.

ABSTRACT: Nodding syndrome is a devastating neurological disorder of uncertain aetiology affecting children in Africa. There is no diagnostic test, and risk factors and symptoms that would allow early diagnosis are poorly documented. This study aimed to describe the clinical, electrophysiological and brain imaging (MRI) features and complications of nodding syndrome in Ugandan children. Case series. 22 children with nodding syndrome brought to Mulago National Referral Hospital for assessment. Clinical features, physical and functional disabilities, EEG and brain MRI findings and a staging system with a progressive development of symptoms and complications. The median age of symptom onset was 6 (range 4-10) years and median duration of symptoms was 8.5 (range 2-11) years. 16 of 22 families reported m

SUBMITTER: Idro R 

PROVIDER: S-EPMC3646179 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature