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Click Reaction-Mediated Functionalization of Near-Infrared Pyrrolopyrrole Cyanine Dyes for Biological Imaging Applications.

ABSTRACT: A clickable pyrrolopyrrole cyanine (PPCy) dye was synthesized by incorporating an alkyne moiety, followed by click reaction with azide-functionalized molecules of different polarities. The clickable dyes are readily amenable to labelling diverse molecules and exhibit an exceptionally high photostability and an impressive fluorescence quantum yield.

SUBMITTER: Zhou M 

PROVIDER: S-EPMC3650893 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature

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Click Reaction-Mediated Functionalization of Near-Infrared Pyrrolopyrrole Cyanine Dyes for Biological Imaging Applications.

Zhou Mingzhou M   Zhang Xuan X   Bai Mingfeng M   Shen Duanwen D   Xu Baogang B   Kao Jeffery J   Xia Ge G   Achilefu Samuel S  

RSC advances 20130501 19

A clickable pyrrolopyrrole cyanine (PPCy) dye was synthesized by incorporating an alkyne moiety, followed by click reaction with azide-functionalized molecules of different polarities. The clickable dyes are readily amenable to labelling diverse molecules and exhibit an exceptionally high photostability and an impressive fluorescence quantum yield. ...[more]

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