Systolic blood pressure and incident heart failure in the elderly. The Cardiovascular Health Study and the Health, Ageing and Body Composition Study.

ABSTRACT:

Background

The exact form of the association between systolic blood pressure (SBP) and heart failure (HF) risk in the elderly remains incompletely defined, especially in individuals not receiving antihypertensive drugs.

Objective

To examine the association between SBP and HF risk in the elderly.

Design

Competing-risks proportional hazards modelling of incident HF risk, using 10-year follow-up data from two NIH-sponsored cohort studies: the Cardiovascular Health Study (inception: 1989-90 and 1992-3) and the Health ABC Study (inception: 1997-8).

Setting

Community-based cohorts.

Participants

4408 participants (age, 72.8 (4.9) years; 53.1% women, 81.7% white; 18.3% black) without prevalent HF and not receiving antihypertensive drugs at baseline.

Main outc

SUBMITTER: Butler J 

PROVIDER: S-EPMC3652313 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature