Molecular analysis of Staphylococcus epidermidis strains isolated from community and hospital environments in China.

ABSTRACT:

Background

Staphylococcus epidermidis is a common cause of nosocomial infections worldwide. This study analyzed the differences in genetic endowment and clonal lineages with pathogenesis and resistance traits of S. epidermidis isolates collected from community and hospital environments (patients and healthcare staff) of the same ecological niche, time period, and geographical location in China.

Methodology/principal findings

Molecular epidemiology and population analysis showed that nasal colonization rates of S. epidermidis in the community of Shanghai area of China and in healthcare personnel were 44.8% (methicillin-resistant S. epidermidis, MRSE: 17.2%) and 61.3% (MRSE: 30.0%), respectively. 86.7% of clinical isolates were MRSE. Among the strains studied, 44 sequence type

SUBMITTER: Du X 

PROVIDER: S-EPMC3652868 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature