General synthetic approach to functionalized dihydrooxepines.

ABSTRACT: A three-step sequence to access functionalized 4,5-dihydrooxepines from cyclohexenones has been developed. This approach features a regioselective Baeyer-Villiger oxidation and subsequent functionalization via the corresponding enol phosphate intermediate.

SUBMITTER: Nicolaou KC 

PROVIDER: S-EPMC3653422 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature