Timing of administration of prophylactic antibiotics for caesarean section: a systematic review and meta-analysis.

ABSTRACT:

Background

Prophylactic antibiotics reduce infectious morbidity from caesarean section. The timing of their administration, however, is a matter of controversy.

Objectives

To examine maternal and neonatal infectious morbidity in women receiving preoperative prophylaxis compared with those receiving intraoperative administration.

Search strategy

Medline, Embase, Current Controlled Trials and Cochrane Central were searched from their inception dates to December 2011.

Selection criteria

Randomised controlled trials of a single dose of any antibiotic comparing preoperative with intraoperative administration were selected.

Data collection and analysis

Trial characteristics, outcomes and quality measures, based on the Cochrane tool for risk of bias, were indep

SUBMITTER: Baaqeel H 

PROVIDER: S-EPMC3654161 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature