MmPalateMiRNA, an R package compendium illustrating analysis of miRNA microarray data.

ABSTRACT:

Background

MicroRNAs (miRNAs) constitute the largest family of noncoding RNAs involved in gene silencing and represent critical regulators of cell and tissue differentiation. Microarray expression profiling of miRNAs is an effective means of acquiring genome-level information of miRNA activation and inhibition, as well as the potential regulatory role that these genes play within a biological system. As with mRNA expression profiling arrays, miRNA microarrays come in a variety of platforms from numerous manufacturers, and there are a multitude of techniques available for reducing and analyzing these data.

Results

In this paper, we present an analysis of a typical two-color miRNA microarray experiment using publicly available packages from R and Bioconductor, the open-source

SUBMITTER: Brock GN 

PROVIDER: S-EPMC3654997 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature