Green synthesis of graphene and its cytotoxic effects in human breast cancer cells.

ABSTRACT:

Background

This paper describes an environmentally friendly ("green") approach for the synthesis of soluble graphene using Bacillus marisflavi biomass as a reducing and stabilizing agent under mild conditions in aqueous solution. In addition, the study reported here investigated the cytotoxicity effects of graphene oxide (GO) and bacterially reduced graphene oxide (B-rGO) on the inhibition of cell viability, reactive oxygen species (ROS) generation, and membrane integrity in human breast cancer cells.

Methods

The reduction of GO was characterized by ultraviolet-visible spectroscopy. Size distribution was analyzed by dynamic light scattering. Further, X-ray diffraction and high-resolution scanning electron microscopy were used to investigate the crystallinity of graphene and

SUBMITTER: Gurunathan S 

PROVIDER: S-EPMC3655623 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature