The association between dietary energy density and type 2 diabetes in Europe: results from the EPIC-InterAct Study.

ABSTRACT:

Background

Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake.

Methodology/principal findings

A case-cohort study was nested within the European Prospective Investigation into Cancer (EPIC) study of 340,234 participants contributing 3.99 million person years of follow-up, identifying 12,403 incident diabetes cases and a random subcohort of 16,835 individuals from 8 European countries. DED was calculated as energy (kcal) from foods (except beverages)

SUBMITTER: InterAct Consortium 

PROVIDER: S-EPMC3655954 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature