Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial.

ABSTRACT:

Purpose

Knee osteoarthritis is a common, debilitating chronic disease. Prolotherapy is an injection therapy for chronic musculoskeletal pain. We conducted a 3-arm, blinded (injector, assessor, injection group participants), randomized controlled trial to assess the efficacy of prolotherapy for knee osteoarthritis.

Methods

Ninety adults with at least 3 months of painful knee osteoarthritis were randomized to blinded injection (dextrose prolotherapy or saline) or at-home exercise. Extra- and intra-articular injections were done at 1, 5, and 9 weeks with as-needed additional treatments at weeks 13 and 17. Exercise participants received an exercise manual and in-person instruction. Outcome measures included a composite score on the Western Ontario McMaster University Osteoarthri

SUBMITTER: Rabago D 

PROVIDER: S-EPMC3659139 | biostudies-literature | 2013 May-Jun

REPOSITORIES: biostudies-literature