A comprehensive review of the therapeutic and pharmacological effects of ginseng and ginsenosides in central nervous system.

ABSTRACT: Ginseng is one of the most widely used herbal medicines in human. Central nervous system (CNS) diseases are most widely investigated diseases among all others in respect to the ginseng's therapeutic effects. These include Alzheimer's disease, Parkinson's disease, cerebral ischemia, depression, and many other neurological disorders including neurodevelopmental disorders. Not only the various types of diseases but also the diverse array of target pathways or molecules ginseng exerts its effect on. These range, for example, from neuroprotection to the regulation of synaptic plasticity and from regulation of neuroinflammatory processes to the regulation of neurotransmitter release, too many to mention. In general, ginseng and even a single compound of ginsenoside produce its effects on multipl

SUBMITTER: Kim HJ 

PROVIDER: S-EPMC3659622 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature