Bundle-branch block morphology and other predictors of outcome after cardiac resynchronization therapy in Medicare patients.

ABSTRACT:

Background

Clinical trials of cardiac resynchronization therapy (CRT) have enrolled a select group of patients, with few patients in subgroups such as right bundle-branch block (RBBB). Analysis of population-based outcomes provides a method to identify real-world predictors of CRT outcomes.

Methods and results

Medicare Implantable Cardioverter-Defibrillator Registry (2005 to 2006) data were merged with patient outcomes data. Cox proportional-hazards models assessed death and death/heart failure hospitalization outcomes in patients with CRT and an implantable cardioverter-defibrillator (CRT-D). The 14 946 registry patients with CRT-D (median follow-up, 40 months) had 1-year, 3-year, and overall mortality rates of 12%, 32%, and 37%, respectively. New York Heart Association cla

SUBMITTER: Bilchick KC 

PROVIDER: S-EPMC3659803 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature