Analysis of population substructure in two sympatric populations of Gran Chaco, Argentina.

ABSTRACT: Sub-population structure and intricate kinship dynamics might introduce biases in molecular anthropology studies and could invalidate the efforts to understand diseases in highly admixed populations. In order to clarify the previously observed distribution pattern and morbidity of Chagas disease in Gran Chaco, Argentina, we studied two populations (Wichí and Criollos) recruited following an innovative bio-cultural model considering their complex cultural interactions. By reconstructing the genetic background and the structure of these two culturally different populations, the pattern of admixture, the correspondence between genealogical and genetic relationships, this integrated perspective had the power to validate data and to link the gap usually relying on a singular discipline. Althoug

SUBMITTER: Sevini F 

PROVIDER: S-EPMC3661677 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature