Parathyroid hormone and arterial dysfunction in the multi-ethnic study of atherosclerosis.

ABSTRACT:

Objective

High circulating concentrations of parathyroid hormone (PTH) have been associated with increased risks of hypertension, left ventricular hypertrophy, congestive heart failure and cardiovascular mortality. Impaired arterial function is a potential mechanism for these associations. We tested whether serum PTH concentration is associated with measures of arterial function.

Design

Cross-sectional study.

Participants

A total of 6545 persons without clinical cardiovascular disease participating in the community-based Multi-Ethnic Study of Atherosclerosis.

Measurements

Brachial artery flow-mediated dilation (FMD) as well as aortic pulse pressure and arterial pulse parameters derived from Windkessel modelling of the radial pressure waveform.

Results

Hi

SUBMITTER: Bosworth C 

PROVIDER: S-EPMC3664253 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature