Effect of fish oil on circulating adiponectin: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Context

Seafood long-chain polyunsaturated omega-3 fatty acids (n-3 PUFAs) improve insulin sensitivity in animal experiments, but findings remain inconsistent in humans. Adiponectin is a robust marker for insulin sensitivity and adipocyte function. Whether n-3 PUFAs affect adiponectin in humans is unknown.

Objective

Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, the objective of the study was to perform a systematic review and meta-analysis of randomized, placebo-controlled clinical trials (RCTs) to determine the effect of n-3 PUFA consumption on circulating adiponectin in humans.

Data sources

MEDLINE, EMBASE, CABI (CAB abstracts), Cochrane Central Registry of Controlled Trials, ClinicalTrials.gov, SIGLE, and Faculty of 1000 w

SUBMITTER: Wu JH 

PROVIDER: S-EPMC3667269 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature