Acute Sleep Restriction Reduces Insulin Sensitivity in Adolescent Boys.

ABSTRACT:

Background

Short sleep duration has been linked to impaired glucose metabolism in many experimental studies. Moreover, studies have reported indications of an increased metabolic stress following sleep restriction.

Objective

We aimed to investigate the effects of partial sleep deprivation on markers of glucose metabolism. Additionally, we aimed to investigate if short sleep duration induces a state of endocrine stress.

Design

A randomized crossover design, with 2 experimental conditions: 3 consecutive nights of short sleep (SS, 4 h/night) and long sleep (LS, 9 h/night) duration.

Subjects and measurements

In 21 healthy, normal-weight male adolescents (mean ± SD age: 16.8 ± 1.3 y) we measured pre- and post-prandial glucose, insulin, C-peptide, and glucagon concen

SUBMITTER: Klingenberg L 

PROVIDER: S-EPMC3669075 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature