Design and methods of a multi-site, multi-behavioral treatment trial for menopausal symptoms: the MsFLASH experience.

ABSTRACT:

Background

Behavioral strategies are recommended for menopausal symptoms, but little evidence exists regarding efficacy.

Purpose

Describe design and methodology of a randomized controlled 3 by 2 factorial trial of yoga, exercise and omega-3 fatty acids.

Methods

Women from three geographic areas with a weekly average of ≥14 hot flashes/night sweats, who met exclusion/inclusion criteria, were randomized to 12weeks of: 1) yoga classes and daily home practice; 2) supervised, facility-based aerobic exercise training; or 3) usual activity. Women in each arm were further randomized to either omega-3 supplement or placebo. Standardized training, on-going monitoring, and site visits were adopted to ensure consistency across sites and fidelity to the intervention. Participant a

SUBMITTER: Sternfeld B 

PROVIDER: S-EPMC3670607 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature