Closed-chest transthoracic magnetic resonance imaging-guided ventricular septal defect closure in swine.

ABSTRACT:

Objectives

The aim of this study was to close ventricular septal defects (VSDs) directly through the chest wall using magnetic resonance imaging (MRI) guidance, without cardiopulmonary bypass, sternotomy, or radiation exposure.

Background

Surgical, percutaneous, and hybrid management of VSD each have limitations and known morbidity.

Methods

Percutaneous muscular VSDs were created in 10 naive Yorkshire swine using a transjugular laser catheter. Under real-time MRI guidance, a direct transthoracic vascular access sheath was introduced through the chest into the heart along a trajectory suitable for VSD access and closure. Through this transthoracic sheath, muscular VSDs were occluded using a commercial nitinol device. Finally, the right ventricular free wall was closed

SUBMITTER: Ratnayaka K 

PROVIDER: S-EPMC3670769 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature