A multi-country study of intussusception in children under 2 years of age in Latin America: analysis of prospective surveillance data.

ABSTRACT:

Background

Intussusception (IS) is a form of acute intestinal obstruction that occurs mainly in infants and is usually of unknown cause. An association between IS and the first licensed rotavirus vaccine, a reassortant-tetravalent, rhesus-based rotavirus vaccine (RRV-TV), led to the withdrawal of the vaccine. New rotavirus vaccines have now been developed and extensively studied for their potential association with IS. This study aimed to describe the epidemiology and to estimate the incidence of IS in Latin American infants prior to new vaccine introduction.

Methods

Children under 2 years of age representing potential IS cases were enrolled in 16 centers in 11 Latin American countries from January 2003 to May 2005. IS cases were classified as definite, probable, possible or

SUBMITTER: Saez-Llorens X 

PROVIDER: S-EPMC3672009 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature