Neuroendocrine recovery initiated by cognitive behavioral therapy in women with functional hypothalamic amenorrhea: a randomized, controlled trial.

ABSTRACT:

Objective

To determine whether cognitive behavior therapy (CBT), which we had shown in a previous study to restore ovarian function in women with functional hypothalamic amenorrhea (FHA), could also ameliorate hypercortisolemia and improve other neuroendocrine and metabolic concomitants of in FHA.

Design

Randomized controlled trial.

Setting

Clinical research center at an academic medical university.

Patient(s)

Seventeen women with FHA were randomized either to CBT or observation.

Intervention(s)

CBT versus observation.

Main outcome measure(s)

Circulatory concentrations of cortisol, leptin, thyroid-stimulating hormone (TSH), total and free thyronine (T(3)), and total and free thyroxine (T(4)) before and immediately after completion of CBT or observ

SUBMITTER: Michopoulos V 

PROVIDER: S-EPMC3672390 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature