Comparison of percent density from raw and processed full-field digital mammography data.

ABSTRACT:

Introduction

Mammographic density has been established as a strong risk factor for breast cancer, primarily using digitized film mammograms. Full-field digital mammography (FFDM) is replacing film mammography, has different properties than film, and provides both raw and processed clinical display representation images. We evaluated and compared FFDM raw and processed breast density measures and their associations with breast cancer.

Methods

A case-control study of 180 cases and 180 controls matched by age, postmenopausal hormone use, and screening history was conducted. Mammograms were acquired from a General Electric Senographe 2000D FFDM unit. Percent density (PD) was assessed for each FFDM representation using the operator-assisted Cumulus method. Reproducibility within

SUBMITTER: Vachon CM 

PROVIDER: S-EPMC3672765 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature