Genomic dynamics of transposable elements in the western clawed frog (Silurana tropicalis).

ABSTRACT: Transposable elements (TEs) are repetitive DNA sequences that can make new copies of themselves that are inserted elsewhere in a host genome. The abundance and distributions of TEs vary considerably among phylogenetically diverse hosts. With the aim of exploring the basis of this variation, we evaluated correlations between several genomic variables and the presence of TEs and non-TE repeats in the complete genome sequence of the Western clawed frog (Silurana tropicalis). This analysis reveals patterns of TE insertion consistent with gene disruption but not with the insertional preference model. Analysis of non-TE repeats recovered unique features of their genome-wide distribution when compared with TE repeats, including no strong correlation with exons and a particularly strong negative c

SUBMITTER: Shen JJ 

PROVIDER: S-EPMC3673623 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature