Complex history of the amphibian-killing chytrid fungus revealed with genome resequencing data.

ABSTRACT: Understanding the evolutionary history of microbial pathogens is critical for mitigating the impacts of emerging infectious diseases on economically and ecologically important host species. We used a genome resequencing approach to resolve the evolutionary history of an important microbial pathogen, the chytrid Batrachochytrium dendrobatidis (Bd), which has been implicated in amphibian declines worldwide. We sequenced the genomes of 29 isolates of Bd from around the world, with an emphasis on North, Central, and South America because of the devastating effect that Bd has had on amphibian populations in the New World. We found a substantial amount of evolutionary complexity in Bd with deep phylogenetic diversity that predates observed global amphibian declines. By investigating the entire g

SUBMITTER: Rosenblum EB 

PROVIDER: S-EPMC3677446 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature