Ontology highlight
ABSTRACT:
SUBMITTER: Ross OA
PROVIDER: S-EPMC3677575 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Movement disorders : official journal of the Movement Disorder Society 20111024 14
<h4>Background</h4>Given the overlap between Parkinson's disease and essential tremor, we examined genetic variants in α-synuclein (SNCA) as risk determinants for essential tremor.<h4>Methods</h4>Samples from 661 essential tremor subjects and 1316 control subjects from 4 participating North American sites were included in this study. Parkinson's disease samples (n = 427) were compared against controls. Twenty variants were selected for association analysis within the SNCA locus. Individual logis ...[more]