Tannic acid-dependent modulation of selected Lactobacillus plantarum traits linked to gastrointestinal survival.

ABSTRACT:

Background

Owing to its antimicrobial properties dietary tannins may alter the functional efficacy of probiotic lactobacilli in the gastrointestinal (GI)-tract influencing their growth, viability and molecular adaptation to the intestinal environment.

Methods and findings

The effects of tannic acid on Lactobacillus plantarum WCFS1 were studied by in vitro growth monitoring and visualizing the morphological alteration on the cell wall using transmission electron microscopy. Growth upon tannic acid was characterized by dose-dependent reductions of initial viable counts and extended lag phases. Lag phase-cells growing upon 0.5 mM tannic acid were abnormally shaped and experienced disturbance on the cell wall such as roughness, occasional leakage and release of cell debris, but

SUBMITTER: Reveron I 

PROVIDER: S-EPMC3679024 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature