Blue-light reflectance imaging of macular pigment in infants and children.

ABSTRACT:

Purpose

While the role of the macular pigment carotenoids in the prevention of age-related macular degeneration has been extensively studied in adults, comparatively little is known about the physiology and function of lutein and zeaxanthin in the developing eye. We therefore developed a protocol using a digital video fundus camera (RetCam) to measure macular pigment optical density (MPOD) and distributions in premature infants and in children.

Methods

We used blue light reflectance to image the macular pigment in premature babies at the time of retinopathy of prematurity (ROP) screening and in children aged under 7 years who were undergoing examinations under anesthesia for other reasons. We correlated the MPOD with skin carotenoid levels measured by resonance Raman spectro

SUBMITTER: Bernstein PS 

PROVIDER: S-EPMC3680006 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature