Presence of antibodies against genogroup VI norovirus in humans.

ABSTRACT:

Background

Noroviruses are important enteric pathogens in humans and animals. Recently, we reported a novel canine norovirus (CaNoV) in dogs with diarrhea belonging to a new genogroup (GVI). No data are available on exposure of humans to this virus.

Methods

Sera from 373 small animal veterinarians and 120 age-matched population controls were tested for IgG antibodies to CaNoV by a recombinant virus like particle based enzyme-linked immunosorbent assay.

Results

Antibodies to CaNoV were found in 22.3% of the veterinarians and 5.8% of the control group (p < 0.001). Mean corrected OD450 values for CaNoV antibodies were significantly higher in small animal veterinarians compared to the control group.

Conclusions

These findings suggest that CaNoV may infect humans an

SUBMITTER: Mesquita JR 

PROVIDER: S-EPMC3680240 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature