A semi-automated genome annotation comparison and integration scheme.

ABSTRACT:

Background

Different genome annotation services have been developed in recent years and widely used. However, the functional annotation results from different services are often not the same and a scheme to obtain consensus functional annotations by integrating different results is in demand.

Results

This article presents a semi-automated scheme that is capable of comparing functional annotations from different sources and consequently obtaining a consensus genome functional annotation result. In this study, we used four automated annotation services to annotate a newly sequenced genome--Arcobacter butzleri ED-1. Our scheme is divided into annotation comparison and annotation determination sections. In the functional annotation comparison section, we employed gene synonym li

SUBMITTER: Liu Z 

PROVIDER: S-EPMC3680241 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature