High-throughput screen of essential gene modules in Mycobacterium tuberculosis: a bibliometric approach.

ABSTRACT:

Background

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis). The annotation of functional genome and signaling network in M. tuberculosis are still not systematic. Essential gene modules are a collection of functionally related essential genes in the same signaling or metabolic pathway. The determination of essential genes and essential gene modules at genomic level may be important for better understanding of the physiology and pathology of M. tuberculosis, and also helpful for the development of drugs against this pathogen. The establishment of genomic operon database (DOOR) and the annotation of gene pathways have felicitated the genomic analysis of the essential gene modules of M. tuberculosis.

Method

Bibliometric approach

SUBMITTER: Xu G 

PROVIDER: S-EPMC3680244 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature