MR cine DENSE dyssynchrony parameters for the evaluation of heart failure: comparison with myocardial tissue tagging.

ABSTRACT:

Objectives

We sought to assess the effectiveness of automated mechanical dyssynchrony (MD) parameters based on regional heterogeneity of strain (circumferential [CURE], longitudinal [LURE], and radial uniformity ratio estimates) relative to parameters based on regional time to peak contraction with cardiac magnetic resonance (CMR) cine DENSE (Displacement Encoding with Stimulated Echoes) validated with myocardial tissue tagging (MTT) strain data.

Background

Dyssynchrony measures based on the Fourier transformation (FT) of regional strain, such as CURE (previously evaluated in cardiac resynchronization therapy candidates), directly assess MD and yield straightforward global dyssynchrony indexes; however, performance relative to the 12-segment standard deviation of time to pea

SUBMITTER: Budge LP 

PROVIDER: S-EPMC3680367 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature