Antibody responses in humans infected with newly emerging strains of West Nile Virus in Europe.

ABSTRACT: Infection with West Nile Virus (WNV) affects an increasing number of countries worldwide. Although most human infections result in no or mild flu-like symptoms, the elderly and those with a weakened immune system are at higher risk for developing severe neurological disease. Since its introduction into North America in 1999, WNV has spread across the continental United States and caused annual outbreaks with a total of 36,000 documented clinical cases and ∼1,500 deaths. In recent years, outbreaks of neuroinvasive disease also have been reported in Europe. The WNV strains isolated during these outbreaks differ from those in North America, as sequencing has revealed that distinct phylogenetic lineages of WNV concurrently circulate in Europe, which has potential implications for the developme

SUBMITTER: Chabierski S 

PROVIDER: S-EPMC3680493 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature