Associations of job strain and lifestyle risk factors with risk of coronary artery disease: a meta-analysis of individual participant data.

ABSTRACT:

Background

It is unclear whether a healthy lifestyle mitigates the adverse effects of job strain on coronary artery disease. We examined the associations of job strain and lifestyle risk factors with the risk of coronary artery disease.

Methods

We pooled individual-level data from 7 cohort studies comprising 102 128 men and women who were free of existing coronary artery disease at baseline (1985-2000). Questionnaires were used to measure job strain (yes v. no) and 4 lifestyle risk factors: current smoking, physical inactivity, heavy drinking and obesity. We grouped participants into 3 lifestyle categories: healthy (no lifestyle risk factors), moderately unhealthy (1 risk factor) and unhealthy (2-4 risk factors). The primary outcome was incident coronary artery disease (defi

SUBMITTER: Kivimaki M 

PROVIDER: S-EPMC3680555 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature