Serum C-peptide levels and risk of death among adults without diabetes mellitus.

ABSTRACT:

Background

Connecting peptide (C-peptide) plays a role in early atherogenesis in patients with diabetes mellitus and may be a marker for cardiovascular morbidity and mortality in patients without diabetes. We investigated whether serum C-peptide levels are associated with all-cause, cardiovascular-related and coronary artery disease-related mortality in adults without diabetes.

Methods

We used data from the Third Nutrition and Health Examination Survey (NHANES III) and the NHANES III Linked Mortality File in the United States. We analyzed mortality data for 5902 participants aged 40 years and older with no history of diabetes and who had available serum C-peptide levels from the baseline examination. We grouped the participants by C-peptide quartile, and we performed Cox pro

SUBMITTER: Min JY 

PROVIDER: S-EPMC3680586 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature