Extracting drug-drug interaction from the biomedical literature using a stacked generalization-based approach.

ABSTRACT: Drug-drug interaction (DDI) detection is particularly important for patient safety. However, the amount of biomedical literature regarding drug interactions is increasing rapidly. Therefore, there is a need to develop an effective approach for the automatic extraction of DDI information from the biomedical literature. In this paper, we present a Stacked Generalization-based approach for automatic DDI extraction. The approach combines the feature-based, graph and tree kernels and, therefore, reduces the risk of missing important features. In addition, it introduces some domain knowledge based features (the keyword, semantic type, and DrugBank features) into the feature-based kernel, which contribute to the performance improvement. More specifically, the approach applies Stacked generalizati

SUBMITTER: He L 

PROVIDER: S-EPMC3681788 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature