Can dexmedetomidine be a safe and efficacious sedative agent in post-cardiac surgery patients? a meta-analysis.

ABSTRACT:

Introduction

The aim of this study was to explore the use of dexmedetomidine as a safe and efficacious sedative agent in post-cardiac surgery patients.

Methods

A systematic literature search of MEDLINE, EMBASE, the Cochrane Library and Science Citation Index until January 2012 and review of studies was conducted. Eligible studies were of randomized controlled trials or cohort studies, comparing dexmedetomidine with a placebo or an alternative sedative agent in elective cardiac surgery, using dexmedetomidine for postoperative sedation and available in full text. Two reviewers independently performed study selection, quality assessment, and data extraction.

Results

The search identified 530 potentially relevant publications; 11 met selection criteria in this meta-analys

SUBMITTER: Lin YY 

PROVIDER: S-EPMC3682268 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature