N-3 fatty acid-enriched parenteral nutrition regimens in elective surgical and ICU patients: a meta-analysis.

ABSTRACT:

Introduction

Previous studies and a meta-analysis in surgical patients indicate that supplementing parenteral nutrition regimens with n-3 polyunsaturated fatty acids (PUFAs), in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), is associated with improved laboratory and clinical outcomes in the setting of hyper-inflammatory conditions. Refined or synthetic fish oils are commonly used as a source of EPA and DHA. The objective of the present meta-analysis was to evaluate n-3 PUFA-enriched parenteral nutrition regimens in elective surgical and intensive care unit (ICU) patients.

Methods

Medline was searched for randomized controlled trials comparing n-3 PUFA-enriched lipid emulsions with standard non-enriched lipid emulsions (i.e. soybean oil, MCT/LCT or ol

SUBMITTER: Pradelli L 

PROVIDER: S-EPMC3682286 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature