Comparison of the vaginal microbiota diversity of women with and without human papillomavirus infection: a cross-sectional study.

ABSTRACT:

Background

The female genital tract is an important bacterial habitat of the human body, and vaginal microbiota plays a crucial role in vaginal health. The alteration of vaginal microbiota affects millions of women annually, and is associated with numerous adverse health outcomes, including human papillomavirus (HPV) infection. However, previous studies have primarily focused on the association between bacterial vaginosis and HPV infection. Little is known about the composition of vaginal microbial communities involved in HPV acquisition. The present study was performed to investigate whether HPV infection was associated with the diversity and composition of vaginal microbiota.

Methods

A total of 70 healthy women (32 HPV-negative and 38 HPV-positive) with normal cervical cyt

SUBMITTER: Gao W 

PROVIDER: S-EPMC3684509 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature