Monetary reward processing in obese individuals with and without binge eating disorder.

ABSTRACT:

Background

An important step in obesity research involves identifying neurobiological underpinnings of nonfood reward processing unique to specific subgroups of obese individuals.

Methods

Nineteen obese individuals seeking treatment for binge eating disorder (BED) were compared with 19 non-BED obese individuals (OB) and 19 lean control subjects (LC) while performing a monetary reward/loss task that parses anticipatory and outcome components during functional magnetic resonance imaging. Differences in regional activation were investigated in BED, OB, and LC groups during reward/loss prospect, anticipation, and notification.

Results

Relative to the LC group, the OB group demonstrated increased ventral striatal and ventromedial prefrontal cortex activity during anticipat

SUBMITTER: Balodis IM 

PROVIDER: S-EPMC3686098 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature