Increasing incidence of celiac disease in a North American population.

ABSTRACT:

Objectives

The prevalence of celiac disease (CD) varies greatly, potentially because of incomplete ascertainment of cases and small study samples with limited statistical power. Previous reports indicate that the incidence of CD is increasing. We examined the prevalence of CD in a well-defined US county.

Methods

Population-based study in Olmsted County, Minnesota, USA. Using the infrastructure of the Rochester Epidemiology Project, medical, histopathology, and CD serology records were used to identify all new cases of CD in Olmsted County since 2000. Age- and sex-specific and adjusted (to the US white 2000 population) incidence rates for CD were estimated. Clinical presentation at diagnosis was also assessed.

Results

Between 2000 and 2010, 249 individuals (157 female

SUBMITTER: Ludvigsson JF 

PROVIDER: S-EPMC3686116 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature