Results from the Upper Limb International Spasticity Study-II (ULISII):a large, international, prospective cohort study investigating practice and goal attainment following treatment with botulinum toxin A in real-life clinical management.

ABSTRACT:

Objective

To describe real-life practice and person-centred outcomes in the treatment of poststroke upper limb spasticity with botulinum toxin A (BoNT-A).

Design

Observational, prospective study.

Setting

84 secondary care centres in 22 countries.

Participants

456 adults (≥18 years) with poststroke upper limb spasticity treated with one cycle of BoNT-A.

Methods/outcomes

Muscle selection, BoNT-A preparation, injection technique and timing of follow-up were conducted according to routine practice for each centre.

Primary outcome

achievement of the patient's primary goal for treatment using goal-attainment scaling (GAS). Measurements of spasticity, standardised outcome measures and global benefits were also recorded.

Results

The median number o

SUBMITTER: Turner-Stokes L 

PROVIDER: S-EPMC3686177 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature