Fracture risk in older, long-term survivors of early-stage breast cancer.

ABSTRACT:

Objectives

To examine the effect of breast cancer and its treatment on fracture risk in older breast cancer survivors.

Design

A 10-year prospective cohort study beginning 5 years after a diagnosis of breast cancer for survivors and match date for comparison women.

Setting

Six integrated healthcare systems.

Participants

Women aged 65 and older (1,286 survivors, 1,286 comparison women, mean age 77.7 in both groups, white, non-Hispanic: survivors, 81.6%; comparison women, 85.2%) who were alive and recurrence free 5 years after a diagnosis of early-stage breast cancer and matched on age, study site, and enrollment year to a comparison cohort without breast cancer.

Measurements

Cox proportional hazards models were used to estimate the association between frac

SUBMITTER: Pawloski PA 

PROVIDER: S-EPMC3686911 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature